Second Cycle Programmes    (Master's Degree)
Master (with thesis) - Institute of Health Sciences - Pharmaceutical Chemistry
General Description  |  Key Learning Outcomes  |  Course Structure Diagram with Credits
General Description ^
History
The peculiar activity domain of pharmaceutical chemistry department comprises convenient production of active drug ingredients and occasional manufacture of excipients, characterization of their chemical structures and their analysis in addition to researches on drug metabolism and molecular mechanism of action of drugs by means of chemical structure and biological activity. In order to educate well-qualified specialists and researchers with sufficient knowledge on the topics mentioned above the master of science program in Pharmaceutical Chemistry, that has been appertained to Institute of Health Sciences, was established in academic year 1982-1983.
Qualification Awarded
By the achievement of the program the title ‘’master of science’’ is assumed.
Specific Admission Requirements
The students have to comply with the regulations of postgraduate education and training. Bachelor degree in Pharmacy (4 or 5 years education) or Chemistry is required. The students have to pass the digital section of the‘’Academic Staff and the Graduate Entry Examination’’ with the score equivalent to or greater than 60%. The students have to succeed in scientific assessment and interview.
Specific Arrangements For Recognition Of Prior Learning (Formal, Non-Formal and Informal)
Bachelor degree in Pharmacy (4 or 5 years education) or Chemistry is required.
Qualification Requirements and Regulations
The students have to succeed in all courses of master program and master thesis completion exam applied by an academic assessment committee.
Profile of The Programme
The students are taught basic topics in pharmaceutical chemistry, medicinal chemistry, active pharmaceutical ingredients, drug design, production, analysis and metabolism and they are sophisticated as being a researcher in a scientific research project.
Occupational Profiles of Graduates With Examples
Carries on his/her academic career in state and private universities, finds an employment in drug industry (research and development, quality control, production, regulatory affairs), works for national or international research centers as a specialist or project manager.
Access to Further Studies
By the achievement of pharmaceutical chemistry master program and ALES examination (with the examination mark greater than or equal to the mark declared by the institute); the graduate, who has adequate competence on preferred foreign languages (especially English), can apply for the doctorate programes concerning his/her master program or other multidisciplinary programs. If the student succeeds in scientific assessment and interview he/she can attend the doctorate program.
Examination Regulations, Assessment and Grading
The graduation score is composed of mid-term assessments (mid-term exam, housework, project) by the ratio of 40% and final assessments (final exam, housework, project) by the ratio of 60%. The students have to succeed in master thesis completion exam applied by an academic assessment committee.
Graduation Requirements
The program comprises at least 21 local credits from at least 7 lessons, 1 seminar course, master of science (MSc) thesis completion exam. The MSc program includes compulsory and elective courses with the total 60 AKTS credits. Together with mid-term and final exams; education activities as report preparation and homeworks, quizes, presentations and demonstrative works, participation in projects could be taken into consideration by means of performance appraisal of the studuent. The students have to pass exams of each course with the score equivalent to or greater than 65%. If the student completes a course with failure he/she can register at the same course for a second time or register at different MSc courses approved by his/her advisor. The student can apply at most two undergraduate courses that had not been applied during the student’s undergraduate education. The seminar course and thesis work have no credits in the local credit system and have been depicted as successfull or failure in the transcript. The student has to apply for the course that regulates his/her work on the thesis as from the beginning of third semester at the latest. The student has to write the results of his/her MSc thesis work in accordance with the concerned institute’s guidebook that denotes the rules of wording and also the student has to present his/her MSc thesis orally in the presence of an academic assessment committee. Following this presentation the academic assessment committee take a decision by simple majority on the thesis either acceptance or refusal and also the academic assessment committee has the right to postulate a correction within context of the thesis.If the academic assessment committee claim for correction the student has to review his/her thesis and prepare an adequate version during six months and the student has to present his/her MSc thesis again, in the presence of the same academic assessment committee. If the academic assessment committee refuses the reviewed thesis the student’s subscription will be abrogated 
Mode of Study (Full-Time, Part-Time, E-Learning )
Full-Time
Address, Programme Director or Equivalent
Marmara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry Tıbbiye Street No: 49 Haydarpaşa 34668 İSTANBUL Prof.Dr. İlkay Küçükgüzel (Tel : 0216 349 12 16 – e-mail : ikucukguzel@marmara.edu.tr
Facilities
The Department is well equipped with modern research instrumentation and equipment in the areas of organic synthesis, spectroscopic (UV and IR Spectrophotometer) and chromatographic (liquid chromatograph with PDA detector) analysis, drug metabolism and literature research (permanent internet, ScienceDirect and WOS database Access). Marmara University Scientific Research Projects Commission supports master thesis.
Key Learning Outcomes ^
1 A succesful graduate of this program : has the knowledge on chemical structure, nomenclature and properties of raw materials and related compounds used in pharmaceutical manifacturing.
2 has the knowledge on mechanism of drug action and structure-activity relationships.
3 has the knowledge on current approaches used in rational drug design as well as classical methods for the development of novel drug molecules.
4 has the knowledge about biotransformation mechanisms of the drugs, identification of the potential metabolites, development of prodrugs, pharmacological and toxicological consequences of these reactions.
5 has the knowledge and the practical skills for organic reaction mechanisms for a beter understanding of medicinal chemistry
6 has the knowledge on organic synthesis methods utilized for the manifacturing of active pharmaceutical ingredients and related compounds.
7 has the competence for the application of instrumental analysis techniques for the identification and characterization of drug substances using spectral analyses.
8 can apply and develop spectral and chromatographic analysis techniques for the quantification of drug substances in bulk material, pharmaceutical products and biological fluids.
9 has knowledge about chemical stability and interactions of pharmaceutical raw materials ; determines the problems about pharmaceutical impurities and provides solutions.
10 can make literature search and reach to the sources about medicinal chemistry and related topics; makes contribution to the solution by interpretation and application of these data in the required fields.
11 reachs the level to be involved in a research or project in the above mentioned fields, under supervision of an advisor.
12 is an eligible individual for team work in a group of researchers from different disciplines of pharmaceutical field.
13 keeps his/her knowledge about developments up to date by following the domestic and international sources.
Course Structure Diagram with Credits ^
T : Theoretical P: Practice
No Course Unit Code Course Unit Title Type of Course T P ECTS
1 FMK701 Nomenclature of Organic Compounds Compulsory 3 0 6
2 FMK-S1..4-YL Elective - 1..4 Elective 12 0 24
Total 15 0 30
No Course Unit Code Course Unit Title Type of Course T P ECTS
1 FMK700 Seminar Compulsory 0 2 5
2 FMK702 Searching For Scientific Resources Compulsory 2 2 5
3 FMK704 Organic Reactions Compulsory 2 2 5
4 FMK-S4,5,6-YL Elective - 4-5-6 Elective 9 0 15
Total 13 6 30
No Course Unit Code Course Unit Title Type of Course T P ECTS
1 Thesis Compulsory 60

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